2025-26 Women’s First Round Odds: Spreads, Lines for all 32 Games

The women’s path to cutting down the final net begins this weekend.

The women’s NCAA Tournament begins Friday and carries into Monday. Let’s check out the odds for each first-round game at DraftKings Sportsbook as of March 20.

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FRIDAY, MARCH 20

No. 16 Missouri State vs. No. 1 Texas

Spread: Texas -44.5
Moneyline: TBD
O/U: 134.5

No. 15 Jacksonville vs. No. 2 LSU

Spread: LSU -51.5
Moneyline: TBD
O/U: 162.5

No. 15 Holy Cross vs. No. 2 Michigan

Spread: Michigan -41.5
Moneyline: TBD
O/U: 130.5

No. 14 UC San Diego 40, No. 3 TCU 86

Spread: TCU -34.5 (TCU covers)
O/U: 130.5 (Under hits)

No. 14 Charleston 64, No. 3 Duke 81

Spread: Duke -34.5 (Charleston covers)
O/U: 131.5 (Over hits)

No. 13 Western Illinois vs. No. 4 UNC

Spread: UNC -25.5
Moneyline: UNC -50000; Western Illinois +4000
O/U: 132.5

No. 13 Green Bay vs. No. 4 Minnesota

Spread: Minnesota -21.5
Moneyline: Minnesota -9000; Green Bay +2500
O/U: 123.5

No. 13 Idaho vs. No. 4 Oklahoma

Spread: Oklahoma -34.5
Moneyline: TBD
O/U: 158.5

No. 12 Murray State vs. No. 5 Maryland

Spread: Maryland -30.5
Moneyline: TBD
O/U: 165.5

No. 12 Gonzaga vs. No. 5 Ole Miss

Spread: Ole Miss -14.5
Moneyline: Ole Miss -1350; Gonzaga +800
O/U: 135.5

No. 12 Colorado State vs. No. 5 Michigan State

Spread: Michigan State -18.5
Moneyline: Michigan State -3600; Colorado State +1500
O/U: 133.5

No. 11 South Dakota State 54, No. 6 Washington 72

Spread: Washington -5.5 (UW covers)
O/U: 131.5 (Under hits)

No. 11 Nebraska vs. No. 6 Baylor

Spread: Nebraska -1.5
Moneyline: Nebraska -135, Baylor +114
O/U: 139.5

No. 10 Tennessee vs. No. 7 NC State

Spread: NC State -1.5
Moneyline: NC State -125; Tennessee +105
O/U: 151.5

No. 10 Villanova vs. No. 7 Texas Tech

Spread: Texas Tech -1.5
Moneyline: Texas Tech -135; Villanova +114
O/U: 129.5

No. 9 Virginia Tech 60, No. 8 Oregon 70

Spread: Oregon -3.5 (Oregon covers)
O/U: 138.5 (Under hits)

SATURDAY, MARCH 21

No. 16 Southern vs. No. 1 South Carolina

Spread: South Carolina -52.5
Moneyline: TBD
O/U: 130.5

No. 16 UTSA vs. No. 1 UConn

Spread: UConn -54.5
Moneyline: TBD
O/U: 123.5

No. 16 Cal Baptist vs. No. 1 UCLA

Spread: UCLA -51.5
Moneyline: TBD
O/U: 146.5

No. 15 High Point vs. No. 2 Vanderbilt

Spread: Vanderbilt -36.5
Moneyline: TBD
O/U: 148.5

No. 15 Fairleigh Dickinson vs. No. 2 Iowa

Spread: Iowa -31.5
Moneyline: TBD
O/U: 128.5

No. 14 Howard vs. No. 3 Ohio State

Spread: Ohio State -38.5
Moneyline: TBD
O/U: 142.5

No. 14 Vermont vs. No. 3 Louisville

Spread: Louisville -26.5
Moneyline: Louisville -100000; Vermont +5000
O/U: 121.5

No. 13 Miami OH vs. No. 4 West Virginia

Spread: West Virginia -25.5
Moneyline: West Virginia -50000; Miami OH +4000
O/U: 124.5

No. 12 James Madison vs. No. 5 Kentucky

Spread: Kentucky -15.5
Moneyline: Kentucky -2100; James Madison +1100
O/U: 129.5

No. 11 Fairfield vs. No. 6 Notre Dame

Spread: Notre Dame -9.5
Moneyline: Notre Dame -500, Fairfield +380
O/U: 138.5

No. 11 Rhode Island vs. No. 6 Alabama

Spread: Alabama -9.5
Moneyline: Alabama -550; Rhode Island +410
O/U: 120.5

No. 10 Colorado vs. No. 7 Illinois

Spread: Illinois -3.5
Moneyline: Illinois -175; Colorado +145
O/U: 132.5

No. 10 Virginia vs. No. 7 Georgia

Spread: Georgia -1.5
Moneyline: Georgia -125, Virginia +105
O/U: 131.5

No. 9 Syracuse vs. No. 8 Iowa State 

Spread: Iowa State -7.5
Moneyline: Iowa State -340; Syracuse +270
O/U: 149.5

No. 9 Princeton vs. No. 8 Oklahoma State

Spread: OKlahoma State -6.5
Moneyline: Oklahoma State -278, Princeton +225
O/U: 136.5

No. 9 USC vs. No. 8 Clemson

Spread: USC -5.5
Moneyline: USC -250; Clemson +205
O/U: 120.5